アプリケーション（分析目的）

- Applications for Reseach, Development and Process Analysis -

Topics

NEW AN138
Combined Optical and Atomic Force Microscopy

Correlation between fluorescence intensity and specific AFM force measurements on living Hela cells. A tip was functionalized with a toxin able to target any inositol-containing molecule. Fluorescent cells over-express GPI-anchored proteins and exhibit a high number of specific unbinding events (yellow retraction curve) whereas for most of the non-fluorescent cells, no event (red retraction curve), or a much lower number, can be detected.

NEW AN134
Survey, Screening, Dynamics: A No-Compromise Approach to High-Speed Atomic Force Microscopy

Celgard® oriented Polypropylene membrane (TappingMode, Broadband-A Probe) is a good indicator of AFM force control. Tracking error would cause lateral forces to separate and damage the smaller strands.

NEW AN133-RevA0
Introduction to Bruker's ScanAsyst and PeakForce Tapping AFM Technology

Experimental data of force curves for a cantilever operated in PeakForce Tapping. The lever is driven by a sinusoidal wave and the curves are displayed as force versus time and force versus distance.

1μm scan of Origami DNA in buffer solution using ScanAsyst.

材料
①半導体

※半導体に関する全てのアプリケーションノートはここをクリック

Pick AN127
Nanoscale Charge Transport in LED Materials Using Conducting AFM

Average I-V curves of the three polymer films

Pick AN079
Electrical Characterization with Scanning Probe Microscopes

Height or topography (left), Capacitance (SCM) dC/dV amplitude (middle), and Capacitance (SCM) dC/dV phase (right) images of a conventional Silicon DRAM cell.

AN127 5.4MB Nanoscale Charge Transport in LED Materials Using Conducting AFM
AN079 2MB Electrical Characterization with Scanning Probe Microscopes
AN046 3.3MB Scanning Electron Microscopy and Atomic Force Microscopy Complementary Techniques for High Resolution Surface Investigations
AN027 6.2MB EFM Surface Potential Imaging and Surface Electric Modification with the AFM
②データストレージ

※データストレージに関する全てのアプリケーションノートはここをクリック

Pick AN079
Electrical Characterization with Scanning Probe Microscopes

Topography (left) and tunneling　current (right) images taken on a 1.2nm thin　aluminum oxide (Al2O3) film at a sample bias　voltage of 0.14V. 500nm scans, 5 pA current range. Data courtesy A. Olbrich, Infineon, Munich, Germany.

Pick AN027
EFM Surface Potential Imaging and Surface Electric Modification with the AFM

Topography (left) and FM-EFM (right) images of a　ferroelectric film with electrical bits written onto it.

AN079 2MB Electrical Characterization with Scanning Probe Microscopes
AN027 6.2MB EFM Surface Potential Imaging and Surface Electric Modification with the AFM
③電池

※電池に関する全てのアプリケーションノートはここをクリック

Pick AN132
Simultaneous Electrical and Mechanical Property Mapping at the Nanoscale with PeakForce TUNA

PF-TUNA images of a Li[Ni1/3Mn1/3Co1/3]O2 composite cathode. Sample courtesy of Dr. Zheng and Battaglia, Lawrence Berkeley National Laboratory.

AN132 6.7MB Simultaneous Electrical and Mechanical Property Mapping at the Nanoscale with PeakForce TUNA
AN-AFM02 190KB Investigation of solar cells
④ポリマー

※ポリマーに関する全てのアプリケーションノートはここをクリック

Pick AN133-RevA0
Introduction to Bruker's ScanAsyst and PeakForce Tapping AFM Technology

30μm scan of a Teflon membrane in PeakForce Tapping

Pick AN128
Quantitative Mechanical Property Mapping at the Nanoscale with　PeakForce QNM

Poly(butyl acrylate) brush-like macromolecules(a) Height,(c) Adhesion

AN136 5.3MB Advances in Combined Atomic Force and Raman Microscopy
AN133 4.9MB Introduction to Bruker's ScanAsyst and PeakForce Tapping AFM Technology
AN128 11MB Quantitative Mechanical Property Mapping at the Nanoscale withPeakForce QNM
AN105 4.1MB Advanced Nanoscale Characterization with the Innova Scanning Probe Microscope
AN084 1.3MB Applications of Atomic Force Microscopy for Polymers
AN046 3.3MB Scanning Electron Microscopy and Atomic Force Microscopy Complementary Techniques for High Resolution Surface Investigations
AN022 6MB Applications of Atomic Force Microscopy for Contact Lens Manufacturing
AN013 4.7MB Nanoindenting Scratching and Wear Testing with the Atomic Force Microscope
AN005 6.3MB Lateral and Chemical Force Microscopy Mapping Surface Friction and Adhesion
⑤バイオ

※バイオに関する全てのアプリケーションノートはここをクリック

Pick AN138
Combined Optical and Atomic Force Microscopy

Correlation between fluorescence intensity and specific AFM force measurements on living Hela cells. A tip was functionalized with a toxin able to target any inositol-containing molecule. Fluorescent cells over-express GPI-anchored proteins and exhibit a high number of specific unbinding events (yellow retraction curve) whereas for most of the non-fluorescent cells, no event (red retraction curve), or a much lower number, can be detected.

Pick AN131
BioScope Catalyst: Accessing All Biological Size Scales with High-Resolution AFM Imaging

A　250nm AFM Topography image of a single herpes simplex virus　capsid.　Sample courtesy of Wouter Roos and Gijs Wuite, Vrije Universiteit, Amsterdam, Netherlands.

Pick AN125
Characterizing the Effect of Anticytoskeletal Drugs on Living Cells Using
MIRO and BioScope Catalyst

In the MIRO canvas, the fluorescence image is used as a background to target AFM measurements.

AN138 3.2MB Combined Optical and Atomic Force Microscopy
AN137 6.6MB Performing Enhanced Multiparameter Cell Imaging with Combined Fluorescence Lifetime Imaging Microscopy and Atomic Force Microscopy
AN135 2.9MB Quantitative Imaging of Living Biological Samples by PeakForce QNM Atomic Force Microscopy
AN133 4.9MB Introduction to Bruker's ScanAsyst and PeakForce Tapping AFM Technology
AN131 2.6MB BioScope Catalyst: Accessing All Biological Size Scales with High-Resolution AFM Imaging
AN130 1.9MB Common Approaches to Tip Functionalization for AFM-Based Molecular Recognition Measurements
AN126 376KB Functional Imaging-Using SPM to Visualize Enzymes at Submolecular Resolution AFM
AN125 6.1MB Characterizing the Effect of Anticytoskeletal Drugs on Living Cells Using MIRO and BioScope Catalyst
AN122 4.5MB Ultrastructure and Force Property Measurements of Wheat Grain Tissues Using HarmoniX Mode in Fluid
AN120 2.6MB Advances toward Medical Nano-Imaging by High-Resolution Atomic Force Microscopy
AN117 1.2MB Atomic Force Microscopy and Neurodegenerative Diseases Part 1
AN118 1.5MB Atomic Force Microscopy and Neurodegenerative Diseases Part 2
AN111 3.4MB Atomic Force Microscopy Detecting Specific Ligand-Receptor Interactions on Live Cancer Cells in situ AFM
AN110 1.4MB Drug Interactions Investigated Using Atomic Force Microscopy with Functionalized Tips
AN092 1.4MB Atomic Force Microscopy Imaging and Force Spectroscopy of Individual Bacterial Adhesions
AN089 1.3MB Probing DNA-Protein Interactions with Atomic Force Microscopy
AN077 2MB Drug Dissolution Studies with Atomic Force Microscopy
AN067 1.5MB Atomic Force Microscopy in the Investigation of Gene Delivery Vehicles
AN063 1.8MB Pharmaceutical Studies of Drug Crystal Growth Particles and Coatings
AN056 4.9MB Atomic Force Microscopy in the Pharmaceutical Sciences Drug Interactions and Disease Mechanisms
AN050 1.3MB Atomic Force Microscopy of Microbial Cells
AN049 6MB TappingMode Atomic Force Microscopy Operation in Fluid
AN046 3.3MB Scanning Electron Microscopy and Atomic Force Microscopy Complementary Techniques for High Resolution Surface Investigations
AN044 4.6MB Choosing Atomic Force Microscopy Probes for Biological Applications
AN022 6MB Applications of Atomic Force Microscopy for Contact Lens Manufacturing
AN020 5.2MB Applications of Force Volume Imaging with Atomic Force Microscopes
⑥その他

※その他に関する全てのアプリケーションノートはここをクリック

AN136 5.3MB Advances in Combined Atomic Force and Raman Microscopy
AN134 6.3MB Survey, Screening, Dynamics: A No-Compromise Approach to High-Speed Atomic Force Microscopy
AN133 4.9MB Introduction to Bruker's ScanAsyst and PeakForce Tapping AFM Technology
AN523 317KB Combining Atomic Force Microscopy with Polarized Raman Microscopy
AN128 11MB Quantitative Mechanical Property Mapping at the Nanoscale with　PeakForce QNM
AN107 1.2MB Electrical testing using Torsional Resonance Mode and TUNA AFM
AN087 1.5MB Corrosion Studies with the Atomic Force Microscope Part-1
AN085 3.2MB Scanning Tunneling Microscopy : A Tool for Studying Self-Assemrly and Model Systems for Molecular Devices
AN079 2MB Electrical Characterization with Scanning Probe Microscopes
AN048 4.3MB Scanning Probe Microscopy and Atomic Force Microscopy Technology Overview
AN046 3.3MB Scanning Electron Microscopy and Atomic Force Microscopy Complementary Techniques for High Resolution Surface Investigations
AN028 6.3MB Studies of Metallic Surfaces and Microstructures with Atomic Force Microscopy
AN027 6.2MB EFM Surface Potential Imaging and Surface Electric Modification with the AFM
AN021 4.7MB Using Atomic Force Microscopy for Engineering Low-Scatter Thin Film Optics
AN013 4.7MB Nanoindenting Scratching and Wear Testing with the Atomic Force Microscope
AN011 8MB Phase Imaging Beyond Topography
AN005 6.3MB Lateral and Chemical Force Microscopy Mapping Surface Friction and Adhesion
AN004 3.5MB TappingMode Imaging Applications and Technology
AN-AFM01 270KB AFM and GISAXS Study of Self-assembled FeO Nanoperticles
アプリケーション
①構造（凹凸像）

※構造（凹凸像）に関する全てのアプリケーションノートはここをクリック

Pick AN138
Combined Optical and Atomic Force Microscopy

Correlation between fluorescence intensity and specific AFM force measurements on living Hela cells. A tip was functionalized with a toxin able to target any inositol-containing molecule. Fluorescent cells over-express GPI-anchored proteins and exhibit a high number of specific unbinding events (yellow retraction curve) whereas for most of the non-fluorescent cells, no event (red retraction curve), or a much lower number, can be detected.

Pick AN134
Survey, Screening, Dynamics: A No-Compromise Approach to High-Speed Atomic Force Microscopy

Celgard® oriented Polypropylene membrane (TappingMode, Broadband-A Probe) is a good indicator of AFM force control. Tracking error would cause lateral forces to separate and damage the smaller strands.

Pick AN131
BioScope Catalyst: Accessing All Biological Size Scales with High-Resolution AFM Imaging

AFM phase image of bacterial S-layers from E. coli.　Sample courtesy of Hans Oberleithner, Institute for Physiology II, University of Muenster, Germany

AN138 3.2MB Combined Optical and Atomic Force Microscopy
AN137 6.6MB Performing Enhanced Multiparameter Cell Imaging with Combined Fluorescence Lifetime Imaging Microscopy and Atomic Force Microscopy
AN134 6.3MB Survey, Screening, Dynamics: A No-Compromise Approach to High-Speed Atomic Force Microscopy
AN131 2.6MB BioScope Catalyst: Accessing All Biological Size Scales with High-Resolution AFM Imaging
AN126 376KB Functional Imaging-Using SPM to Visualize Enzymes at Submolecular Resolution
AN125 6.1MB Characterizing the Effect of Anticytoskeletal Drugs on Living Cells Using MIRO and BioScope Catalyst
AN122 4.5MB Ultrastructure and Force Property Measurements of Wheat Grain Tissues Using HarmoniX Mode in Fluid
AN120 2.6MB Advances toward Medical Nano-Imaging by High-Resolution Atomic Force Microscopy
AN117 1.2MB Atomic Force Microscopy and Neurodegenerative Diseases Part 1
AN105 4.1MB Advanced Nanoscale Characterization with the Innova Scanning Probe Microscope : Phase Imaging of Polymer Materials
AN085 3.2MB Scanning Tunneling Microscopy : A Tool for Studying Self-Assembly and Model Systems for Molecular Devices
AN084 1.3MB Applications of Atomic Force Microscopy for Polymers
AN077 2MB Drug Dissolution Studies with Atomic Force Microscopy
AN067 1.5MB Atomic Force Microscopy in the Investigation of Gene Delivery Vehicles
AN063 1.8MB Pharmaceutical Studies of Drug Crystal Growth Particles and Coatings
AN056 4.9MB Atomic Force Microscopy in the Pharmaceutical Sciences Drug Interactions and Disease Mechanisms
AN050 1.3MB Atomic Force Microscopy of Microbial Cells
AN049 6MB TappingMode Atomic Force Microscopy Operation in Fluid
AN046 3.3MB Scanning Electron Microscopy and Atomic Force Microscopy Complementary Techniques for High Resolution Surface Investigations
AN028 6.3MB Studies of Metallic Surfaces and Microstructures with Atomic Force Microscopy
AN022 6MB Applications of Atomic Force Microscopy for Contact Lens Manufacturing
AN021 4.7MB Using Atomic Force Microscopy for Engineering Low-Scatter Thin Film Optics
AN004 3.5MB TappingMode Imaging Applications and Technology
AN-AFM02 190KB Investigation of solar cells
AN-AFM01 270KB AFM and GISAXS Study of Self-Assembled FeO Nanoperticles
②機械特性

※機械特性に関する全てのアプリケーションノートはここをクリック

Pick AN138
Combined Optical and Atomic Force Microscopy

Correlation between fluorescence intensity and specific AFM force measurements on living Hela cells. A tip was functionalized with a toxin able to target any inositol-containing molecule. Fluorescent cells over-express GPI-anchored proteins and exhibit a high number of specific unbinding events (yellow retraction curve) whereas for most of the non-fluorescent cells, no event (red retraction curve), or a much lower number, can be detected.

Pick AN128
Quantitative Mechanical Property Mapping at the Nanoscale with　PeakForce QNM

Cooling of polymer blend of syndiotactic polypropylene and polyethylene　oxide.　g-i show the modulus.

AN138 3.2MB Combined Optical and Atomic Force Microscopy
AN137 6.6MB Performing Enhanced Multiparameter Cell Imaging with Combined Fluorescence Lifetime Imaging Microscopy and Atomic Force Microscopy
AN135 2.9MB Quantitative Imaging of Living Biological Samples by PeakForce QNM Atomic Force Microscopy
AN133 4.9MB Introduction to Bruker's ScanAsyst and PeakForce Tapping AFM Technology
AN132 6.7MB Simultaneous Electrical and Mechanical Property Mapping at the Nanoscale with PeakForce TUNA
AN131 2.6MB BioScope Catalyst: Accessing All Biological Size Scales with High-Resolution AFM Imaging
AN130 1.9MB Common Approaches to Tip Functionalization for AFM-Based Molecular Recognition Measurements
AN128 11MB Quantitative Mechanical Property Mapping at the Nanoscale with　PeakForce QNM
AN125 6.1MB Characterizing the Effect of Anticytoskeletal Drugs on Living Cells Using MIRO and BioScope Catalyst
AN122 4.5MB Ultrastructure and Force Property Measurements of Wheat Grain Tissues Using HarmoniX Mode in Fluid
AN105 4.1MB Advanced Nanoscale Characterization with the Innova Scanning Probe Microscope : Phase Imaging of Polymer Materials
AN056 4.9MB Atomic Force Microscopy in the Pharmaceutical Sciences Drug Interactions and Disease Mechanisms
AN046 3.3MB Scanning Electron Microscopy and Atomic Force Microscopy Complementary Techniques for High Resolution Surface Investigations
AN028 6.3MB Studies of Metallic Surfaces and Microstructures with Atomic Force Microscopy
AN020 5.2MB Applications of Force Volume Imaging with Atomic Force Microscopes
AN013 4.7MB Nanoindenting Scratching and Wear Testing with the Atomic Force Microscope
AN011 8MB Phase Imaging Beyond Topography
③電気特性

※電気特性に関する全てのアプリケーションノートはここをクリック

Pick AN132
Simultaneous Electrical and Mechanical Property Mapping at the Nanoscale with PeakForce TUNA

PeakForce TUNA images of P3HT:PCBM solar cell with a PEDOT modified ITO/glass anode. Shown are (a) topography, scale 10nm;(b) Cycle-averaged Current, scale 5pA.

AN133 4.9MB Introduction to Bruker's ScanAsyst and PeakForce Tapping AFM Technology
AN132 6.7MB Simultaneous Electrical and Mechanical Property Mapping at the Nanoscale with PeakForce TUNA
AN127 5.4MB Nanoscale Charge Transport in LED Materials Using Conducting AFM
AN107 1.2MB Electrical testing using Torsional Resonance Mode and TUNA
AN087 1.5MB Corrosion Studies with the Atomic Force Microscope Part-1
AN079 2MB Electrical Characterization with Scanning Probe Microscopes
AN027 6.2MB EFM Surface Potential Imaging and Surface Electric Modification with the AFM
④相互作用

※相互作用に関する全てのアプリケーションノートはここをクリック

Pick AN138
Combined Optical and Atomic Force Microscopy

Correlation between fluorescence intensity and specific AFM force measurements on living Hela cells. A tip was functionalized with a toxin able to target any inositol-containing molecule. Fluorescent cells over-express GPI-anchored proteins and exhibit a high number of specific unbinding events (yellow retraction curve) whereas for most of the non-fluorescent cells, no event (red retraction curve), or a much lower number, can be detected.

Pick AN110
Drug Interactions Investigated Using Atomic Force Microscopy with
Functionalized Tips

Imaging and probing of D-Ala-D-Ala sites on living bacteria.

AN138 3.2MB Combined Optical and Atomic Force Microscopy
AN118 1.5MB Atomic Force Microscopy and Neurodegenerative Diseases Part 2
AN111 3.4MB Atomic Force Microscopy Detecting Specific Ligand-Receptor Interactions on Live Cancer Cells in situ AFM
AN110 1.4MB Drug Interactions Investigated Using Atomic Force Microscopy with Functionalized Tips
AN092 1.4MB Atomic Force Microscopy Imaging and Force Spectroscopy of Individual Bacterial Adhesions
AN089 1.3MB Probing DNA-Protein Interactions with Atomic Force Microscopy
AN050 1.3MB Atomic Force Microscopy of Microbial Cells
AN022 6MB Applications of Atomic Force Microscopy for Contact Lens Manufacturing
AN020 5.2MB Applications of Force Volume Imaging with Atomic Force Microscopes
AN005 6.3MB Lateral and Chemical Force Microscopy Mapping Surface Friction and Adhesion
⑤その他

※その他に関する全てのアプリケーションノートはここをクリック

AN137 6.6MB Performing Enhanced Multiparameter Cell Imaging with Combined Fluorescence Lifetime Imaging Microscopy and Atomic Force Microscopy
AN136 5.3MB Advances in Combined Atomic Force and Raman Microscopy
AN134 6.3MB Survey, Screening, Dynamics: A No-Compromise Approach to High-Speed Atomic Force Microscopy
AN133 4.9MB Introduction to Bruker's ScanAsyst and PeakForce Tapping AFM Technology
AN523 317KB Combining Atomic Force Microscopy with Polarized Raman Microscopy
AN130 1.9MB Common Approaches to Tip Functionalization for AFM-Based Molecular Recognition Measurements
AN104 987KB Thermal Noise and Effect of Measurement Bandwidth
AN097 1.2MB NanoScope Software Tools for Force Spectroscopy Data Analysis
AN095 5MB Atomic Force Microscopy made simple
AN090 1.2MB Improving the Accuracy of Atomic Force Microscopy Force Measurements : The Thermal Tune Solution to the Cantilever Spring Constant Problem
AN048 4.3MB Scanning Probe Microscopy and Atomic Force Microscopy Technology Overview
AN044 4.6MB Choosing Atomic Force Microscopy Probes for Biological Applications
ブルカー・エイエックスエス
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ブルカー・エイエックスエスは、ナノプローブテクノロジー第167委員会の企業会員です。 ナノプローブテクノロジー第167委員会とは日本学術振興会の設置する61の産学協力研究委員会の１つであり、走査型プローブ顕微鏡(SPM)の基礎・応用技術の組織的発展を目標に活動しています。
167委員会のHPはこちら　 http://www.npt167.jp/